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Description

Prognostic factors of subthalamic stimulation in Parkinsons disease: A comparative study between short-and long-term effects

(A) Plasma concentration after 1 IV dose (5 mg/kg in 3 mice per group per time point) decreases with time for both liposomal formulations

This shifts substrate preference toward lipids over glucose, increasing reliance on -oxidation and aggravating metabolic stress (van Gerwen et al., 2023)