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Description

In addition to clinical trials, some TCMs, such as Rhodiola rosea , 393 Hippophae rhamnoides , 394 Aesculus chinensis , 395 Portulaca oleracea Linn ( Portulacaceae ), 396 Phlomis younghusbandii Mukerj ( Lamiaceae ), 397 Pueraria lobata , 398 Eleutheroside B , 399 and Notoginsenoside R1 , 400,401 showed promise in preventing HAPE/HACE in rat models by inhibiting the infiltration of inflammatory cells, the production of inflammatory cytokines, and apoptosis/pyroptosis

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367 Interestingly, overexpression of ZIP1 can sensitize the tumorigenic prostate epithelial cells (RWPE2) to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis

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doi: 10.1016/j.cld.2013.09.012 97

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