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What was striking about the T-cell response in the HCWs with abortive infection was the enrichment for T cells targeting the conserved nonstructural proteins of open reading frame 1ab (ORF1ab), which make up the core of the RTC [67]

Managing side effects While semaglutide is generally well-tolerated, potential side effects may occur in some patients as their body adjusts

These observations reinforce the need for well-designed randomised controlled trials (RCTs) to validate the findings and expand the evidence base