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Some research suggests that chronic high-dose L-carnitine supplementation may increase TMAO levels via gut bacteria metabolism, and elevated TMAO has been associated with increased cardiovascular risk in observational studies

Allergic Reactions: Though rare, some people may experience allergic reactions to L-Carnitine, which could include rash, itching, or even more severe reactions like difficulty breathing or swelling of the face, lips, tongue, or throat

Parents of a child with PCD, who are carriers of the defective gene, may excrete two to three times the normal amount of carnitine in their urine

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