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Nevertheless, they activate biochemical cascades that lead to modifications of other proteins

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3.2.1 Fluorophores commonly used to determine mitochondrial membrane potential Available mitochondrial membrane potentiometric dyes for fluorescent imaging include tetramethyl rhodamine methyl ester (TMRM, Figure 3 ) and ethyl ester (TMRE), Rhodamine 123 (Rho123), and the ratiometric dye 5,5,6,6-tetrachloro-1,1,3,3-tetraethylbenzimidazolyl-carbocyanine iodide (JC-1) ( Table 2 )

Moreover, GSPB2 induced both NRF-1 and TFAM expression, and increased mtDNA-CN through a protective effect probably exerted by AMPK-SIRT1-PGC1 axis activation (Bao et al