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275 Oxidized LDL was found to induce ferroptosis by inhibiting the activity of GPX4, and anti-ferroptosis treatment showed good therapeutic effects

Studies have found that significant increases in ROS expression in BPH tissue lead to upregulation of HIF-1 expression through induction of PI3K/AKT and ERK phosphorylation [60]

Thus, ALA, while itself an antioxidant, can also raise the levels of other important antioxidants

Some fortified foods contain B12, such as plant-based milk drinks, yeast extract (Marmite) but the NHS says sources for vegans are limited and a vitamin B12 supplement may be needed. The British Dietetic Association (BDA) recommends the following advice: Long-term vegetarians and vegans should have their vitamin B12 status checked, especially as high folate levels can mask vitamin B12 deficiency, encouraged to consume B12 fortified foods and if required, recommended supplements of around 10 mcg per day to ensure adequate status. Always check in with your doctor if you are vegan and are concerned about your B12 levels, says Dr Michael