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A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in severe cases of chronic fatigue syndrome

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Conversely, excessively high intracellular K + in tumor cells may inhibit the antitumor abilities of tumor-associated macrophages, a process possibly achieved through the readjustment of OXPHOS and glycolysis

5 The interaction mechanism between gut microbiota and ferroptosis in IBD The gut microbiota regulates ferroptosis-related signaling pathways through multiple mechanisms, including (i) remodeling luminal iron availability and epithelial iron handling, (ii) rewiring host antioxidant capacity and lipid peroxidation tone via microbial metabolites, and (iii) modulating mucosal immune programs that determine the ferroptosis threshold of distinct cell types