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Baseline laboratory tests [medians with interquartile range (IQR)]: AST 37U/L (25-60), ALT 50U/L (36-75), GT 51U/L (25-177), PLT 221x10 9 /L (212-270), and 39.1% of patients with FIB-4 1.3

The NLRP3 inflammasome fires up heme-induced inflammation in hemolytic conditions

Many acute studies utilize a completely different exposure pattern with very high CS concentrations, which is not necessarily comparable to the smoking regimen used for chronic studies [22, 23]