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The three machine learning methods mentioned above have been widely used in feature selection and disease biomarker identification, each with its own strengths and limitations

Taken together, these findings indicate a potential relationship between protein oxidation, Ca 2+ regulation, and protein aggregation in ALS (Fig

Moreover, evidence suggests that HIF-2 plays a role in maintaining CSC traits through the activation of WNT and NOTCH signaling 148 by elevating superoxide dismutase (SOD) levels and by reducing mitochondrial reactive oxygen species (ROS) levels 149

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