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According to earlier reports, this specific miRNA is expressed in the gonads of a variety of non-mammalian species, such as chicken, frog, and rainbow trout, suggesting that it has a conserved role in a wide range of vertebrate taxa [116,117,118]

Illustratively, BPC 157 (as an original anti-ulcer peptide, stable in human gastric juice more than 24 h unlike standard growth factors rapidly destroyed, and thereby easy applicable, lethal dose (LD1) not achieved, used to be in ulcerative colitis trials and now multiple sclerosis [3,4,5,6,7,8,9,10,11,12,13,14,15,16,17]), within wound/healing gastrointestinal ulcer relations and angiogenesis is advantageous over standard growth angiogenic factors [7]