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Structural studies including sCT and calcitonin receptor ECD suggest that P28 and P29 were relatively distant from the peptide binding pocket of the calcitonin and amylin receptor ECDs and that adding bulky residues would not create steric hindrance for peptide binding [15,27]

Discussion and conclusions Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare types of severe drug hypersensitive reactions with high mortalities (4.8% for SJS and 14.8% for TEN, respectively) [10]

Riccardi J, Ham N, Farber N, Brown L, Abouayred M, Antonoff MB