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Lactylation, a post-translational modification (PTM) identified in 2019, introduces a novel mechanism by which lactate can modulate protein function and gene expression [3]

In the SEARCH for Diabetes in Youth (SEARCH) study, youth with T2D were found to have significantly higher urinary albumin-to-creatinine ratios than youth with T1D (126), and this difference remained significant after multivariable adjustment for obesity, hypertension, and dyslipidemia, all known risk factors for DKD that are more prevalent in youth with T2D vs

Therefore, we concluded that a moderate increase of temperature (20C to 27C) has only a mild effect on the cytosolic redox state, but that an intense temperature increase (20C to 37C) impact the cytosolic redox state

10.2215/CJN.08511109 32 HegglandE