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Description

Apc-mutated intestinal tumors lacking Stard7 are sensitive to mTORC1 inhibition Given the fact that intestinal tumors arising from constitutive Wnt signaling and lacking Stard7 show enhanced mTORC1 signaling, we hypothesized that these malignancies would be very sensitive to mTORC1 pharmacological inhibition

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J Formos Med Assoc 114(3):216220

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We used a high-throughput, phenotypic screening in Caenorhabditis elegans to search for compounds that increased accumulation of a GFP-tagged C

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As the body ages, natural antioxidant production declines

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