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doi: 10.1590/0001-3765202420230559 35

During EMT conversion, activated Zeb1 increases the synthetic levels of PUFAs, which increases the levels of active lipid peroxides, enhancing the sensitivity of tumor cells to ferroptosis

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3.7 Cutting-edge directions and future prospects of astrocytic metabolism research In conclusion, while astrocytes have long been recognized for their supportive roles in the brain, current research is increasingly highlighting their active participation in brain energy metabolism and their potential involvement in neurological disorders