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Besides changes in the mitochondria, it has been shown that older animals have lower number of granulosa cells (GC, cells surrounding the oocyte and supporting the growth of the oocyte) and these cells express lower CoQ10 expression levels

Mol Breed 9:93101 Vernoux T, Wilson RC, Seeley KA, Reichheld JP, Muroy S, Brown S, Maughan SC, Cobbett CS, Van Montagu M, Inze D (2000) The ROOT MERISTEMLESS1 / CADMIUM SENSITIVE2 gene defines a glutathione-dependent pathway involved in initiation and maintenace of cell division during postembryonic root development

As a result, oxidative stress and tissue damage can occur

It's not a magic bullet, but it definitely feels like it supports my weight management efforts and gives me sustained energy throughout my day