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These infants required ventilatory support and high concentrations of supplemental oxygen therapies that induced lung damage with regions of atelectasis and regions of hyperinflation, epithelial injury, hyperplasia of airway smooth muscle, fibrosis, and pulmonary vascular hypertension

doi: 10.1016/j.biochi.2016.04.010 80

Patients should receive clear instructions covering dose measurement, hand hygiene, injection technique, site rotation, refrigeration or storage, missed doses, sharps disposal, and what to do if a reaction occurs

The crude LBNP-PC suspension was centrifuged at 50,000g for 1 h at 4 C to collect sediments, which were then resuspended in 1 mL phosphate-buffered saline (PBS) and filtered through a 0.22 m syringe filter for sterilization