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After a period of time, they found that the selenium deficient animals developed severe heart pathology, while the selenium adequate animals did not develop heart pathology

It also plays a major role in detoxifying chemicals in the liver via a series of enzymes which transform hormones and chemicals into water-soluble elements that can be excreted through the intestines, kidneys and skin

While its strength in a high-coverage of predicted reactions, only a very small portion of them can be experimentally validated in organisms of interest

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