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This small molecule has been demonstrated to prevent HIF-1 from binding to the promoter of VEGF, specifically to the (5-CGTG-3) sequences on hypoxia response elements [107]

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Additionally, we believe that the current practice of medicine would allow for variation in clinical attributes as well as judgment and discernment by the referring practitioner regarding the clinical status of the individual when determining the need for consultation with other practitioner types, including the dentist

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