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Mol Biol Rep 51(1):833

Activated microglia in MS and EAE are associated with the production of several pro-inflammatory cytokines (IL-6, IL-1, IL-18, IL-12, IL-23, TNF-) and chemokines (CCL2, CCL3, CCL4, CCL5, CCL7, CCL12) (135)

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MSNs can also be combined with mitochondria targeting strategies such as DLC or MPP to further improve the targeting effect of drugs in tumor mitochondria