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Figure 5 5 Relationship of ApoE with other neurodegenerative diseases Numerous studies have demonstrated the multifaceted impact of ApoE alleles on neurodegenerative diseases

Cells 11 (4), 590

For example, studies show that LPS upregulates ACSL4 expression in esophageal tissue by activating the transcription factor specificity Protein 1 (Sp1), thereby mediating ferroptosis and mucosal injury (Liu et al., 2022b)