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Notably, Proteobacteria (Pseudomonadota) harboring the phenylpyruvate decarboxylase (PPDC) gene are regarded as the primary contributors to PAGln production in patients with Crohns disease (CD) (124)

Its cardinal role is to support the natural detoxification process: helping cells get rid of the metabolic waste they generate

For the comprehensive knowledge of external-stimuli viz light, thermal, ultrasound, magnetic field, and electric field responsive systems, and non-cleavable systems viz charge inversion, polarity variation, expansion and shrinking, see the review articles by Deng et al