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doi: 10.1126/science.1223490 88 ONeilLJOliveiraCBWangXNavarreteMBarrera-VargasAMerayo-ChalicoJet al

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Ybarra DE, Calienni MN, Ramirez LFB, Frias ETA, Lillo C, del Alonso S V, et al

Mechanistically, CB-839 elevates the levels of intracellular ROS, enhances the movement of Nrf2 into the nucleus, leading to an increase in uridine phosphorylase 1 (UPP1) mRNA expression