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154,155 According to a recent research, KD delayed tumor growth but meanwhile accelerated cachexia onset, therefore shortening survival in a mouse model of IL-6-producing cancer

Chen X, Ji B, Han B, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Grignard E., Hkansson H., Munn S

This trafficking blockade directly reduces surface presentation of HBV peptide-MHC I complexes, as demonstrated in HBV models in which acetaldehyde selectively suppresses MHC I surface expression through organelle dysfunction