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4.4 Dermatomyositis DM, an inflammatory myopathy that primarily affects skin and muscle tissues, is prevalent among young individuals and adults

Current experiments rely on SOD1 transgenic models, which do not recapitulate mitochondrial complex IV deficiency or the genetic heterogeneity of sporadic ALS (such as C9orf72 repeat expansion) and do not assess spinal cord targeting or pharmacokinetic limitations of ferroptosis inhibitors, including low solubility and short half-life

Some GHS-R1a agonists increase appetite (GHRP-6 is notorious for this), while others like ipamorelin produce minimal appetite stimulation

Electrophoresis 23(1), 7480 (2002)