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Its largely due to the treatments (antiretroviral therapies), which can lead to a preferential accumulation of visceral fat through a mix of mechanisms, including causing mitochondrial dysfunction and insulin resistance

Model and physiological GSSR substrates are, for example, l-cysteine-glutathione disulfide (GSSCys) 915 , coenzyme A-glutathione disulfide 3,16 , as well as S -glutathionylated serum albumin 9,11,1720 , sirtuin 21 , sulfiredoxin 22 , and peroxiredoxins 2329