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10.1038/nrneurol.2010.71 52 SerafiniG.PompiliM.InnamoratiM.DwivediY.BrahmachariG.GirardiP

The release of extracellular NLRP3 inflammasome particles from injury hepatocytes can activate HSCs to express IL-1 and -smooth muscle actin (-SMA) proteins, leading to liver inflammation and fibrosis [89]