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Since PD patients are frequently on multiple therapies, it will be important for future studies to determine the independent effect of these therapies on the gut microbiome and their potential roles in the progression and management of the disease

Abstract Epidermal growth factor receptor (EGFR) inhibitors such as erlotinib are novel effective agents in the treatment of EGFR-driven lung cancer, but their clinical impact is often impaired by acquired drug resistance through the secondary T790M EGFR mutation