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However, the precise mechanism by which NMT1 integrates into the dynamic environment of the translating ribosome, and how its co-translational activity is coordinated with that of both human MetAPs and other ribosome-associated enzymes remain unclear

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Genetic analysis reveals AMPK is required to support Tumor Growth in Murine Kras-Dependent Lung Cancer models

Preclinical acute toxicity is low, with reported rodent LD50 values well above any human-equivalent research dose