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Unlike many other receptor tyrosine kinases, dimerization is not a mechanism of activation for the IGF-1R family

Normal alkaline phosphatase and gamma-glutamyltranspeptidase levels can help to distinguish Rotor syndrome from disorders connected with biliary obstruction

The c-terminal half of p100, that is often referred to as IB, also functions as an inhibitor

Second, the increase in HPA-axis sensitivity and reactivity occurring during adolescence may promote an increase in metabolic demand and the generation of ROS, leading to a compensatory increase in the activity of detoxifying enzymes in females [25]