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[3] Lipoic acid is the cofactor of the following enzymes in humans: [12] [13] [14] The most-studied of these is the pyruvate dehydrogenase complex

doi: 10.1186/s12979-017-0087-2 8 SimpsonRJCampbellJPGleesonMKrgerKNiemanDCPyneDBet al

While this method may be less effective than oral or injectable forms, it can be used in conjunction with other treatments for enhanced skincare results