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Management of increased intracranial pressure is similar to that for any other neurologic disorder causing increased intracranial pressure, including elevation of the head of the bed, hyperventilation (if patient is mechanically ventilated), mannitol, and other diuretics

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Treatment of mice with citrate, saline, Di-Vetelact, or standard mouse feed pellets For citrate treatment, mice were injected intraperitoneally once per day with 77 mg/kg citrate solution (made up of 693 mg trisodium citrate, 77 mg citric acid, and 600 mg sodium in 100 ml H 2 O) from postnatal days 14 to 28, along with standard mouse feed pellets and drinking water

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