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Tesofensine side effects can include dry mouth, difficulty sleeping, anxious feelings, increased blood pressure, and serotonin syndrome (if combined with antidepressant medication.) Who should NOT use Tesofensine

Studies have demonstrated that chronic administration of AOD-9604 leads to adaptive changes in adipose tissue, including increased expression of beta-3 adrenergic receptors and enhanced sensitivity to lipolytic signals

Conversely, although the alcohol levels decreased, the difference was not statistically significant

Evidence snapshot Human: no exact-name ClinicalTrials.gov record was located at the July 12, 2026 research cutoff