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Nat Comput Sci

Outcomes would be measured with validated instruments: instrumental elasticity and firmness, corneometry and cutometry, standardized photography with blinded grading, and, most convincingly, dermal biopsies quantifying collagen density and organization before and after

Diabetes (type 1 or type 2) or any condition involving glucose dysregulation

These systems often deliver antigens and adjuvants or cyclic dinucleotide STING agonists within lipid or polymeric carriers, aiming to enhance dendritic cell uptake, support type I interferon responses and improve the depth of response when combined with checkpoint blockade [76, 77, 81]