glutathione synthetase cofactor Overview of de novo synthesis . Reduced glutathione or GSH playing a crucial role in protecting against oxidative stress and free radicals Biosynthetic pathway of glutathione. |

The result of the cell viability assay, LDH leakage assay and lipid peroxidation assay suggests that synergistic action of GSH and vitamin E is more protective than GSH or Vitamin E alone treatment (Fig

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The activity of all these transcription factors, together with the forkhead box class O (FoxO) family of multifunctional transcription factors, regulates redox status and is implicated in the mechanism of carcinogenesis (Brown And Webb 2018)