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In clinical studies, treatment with recombinant IGF-1 improved renal function in patients with moderate renal insufficiency or end stage renal disease (ESRD), as evidenced by increased GFR, lower plasma creatinine and BUN levels, and enhanced inulin clearance

Six years ago, the concept of GLP-1s was so foreign to everybody until there were large clinical trials with them, and now theyre everywhere. Still, some physicians embrace the modality despite the lack of human studies

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