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Some research has shown that GO exhibits more potent antibacterial properties than rGO due to its higher surface charge and functional groups 241,242

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However, niacin differs from nicotinamide in that it can cause a temporary "niacin flush." This flush is characterized by a warm, tingling sensation and reddening of the skin, which occurs due to the widening of blood vessels

In summary, CUR-PP represents a multi-modal, synergistic, and translationally viable neurotherapeutic strategy, combining molecular, cellular, and behavioral benefits with enhanced bioavailability and CNS delivery, and may form the basis for next-generation adjunctive therapies for neurodegenerative diseases