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1 This makes it difficult to perform activities that require skill and concentration, or where the safety of others is involved

The treatment is very tolerable thanks to topical numbing

It will be interesting to investigate whether persistent BCL-2 expression in AR cyto CRPC cells is caused by, in addition to the loss of AR-mediated BCL-2 repression, signaling functions of cytoplasmic AR and/or by other nuclear TFs such as NF-B, STAT33 and E2F1