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doi: 10.1038/ng.3117 66 LiuC

PMID: 34444972

501 During the initial phase, PAMPs and DAMPs generated by pretreatment chemotherapy or radiation therapy regimens are detected by innate immune receptors like TLRs, resulting in the secretion of pro-inflammatory cytokines (e.g., TNF, IL-1, and IL-6) and subsequent activation of host antigen-presenting cells (Fig