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Mesenchymal stem cell-based nanoparticles and scaffolds in regenerative medicine

Studies show that iron-sag markers can be traced in cellular and animal models of neurodegenerative diseases ( in vitro assay, ferroptosis is associated with reduced expression of SLC7A11 and GPX4 proteins, as well as ROS accumulation in corticosterone-constructed hippocampal progenitor neurons ( in vitro and reverses the expression of the proteins mentioned above (Xu C

PLGA nanoparticles have demonstrated ability to cross BBB through PEGylation, size/surface charge tuning, and receptor mediated targeting

Following incubation with 5 L of Annexin V-FITC and 5 L of 7-AAD solution in the dark at room temperature for 15 min, 400 L of binding buffer was added, and the mixture was shaken slightly