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Then, the core clock gene BMAL1 has been shown to act as a negative regulator of the target of rapamycin complex 1 (mTORC1), which acts as a master switch between cell anabolic and catabolic programs, thereby suppressing anabolism 82

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Endo H, Niioka M, Kobayashi N, Tanaka M, Watanabe T (2013) Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis