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doi: 10.1111/pcmr.2013.26.issue-5 11 DMelloA.FinlayG

It may also lead to muscle weakness in people with uremia, seizures in those with seizure disorders, and could potentially affect thyroid hormone activity

No analogous synergy rationale has been established for MK-677 in combination with GHRH analogues, though this remains an active area of investigation