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Fully human anti-interleukin-8 monoclonal antibodies: potential therapeutics for the treatment of inflammatory disease states

In addition, auditory nerve degeneration is the first pathological change, and synaptosis and glutamate between hair cells and the auditory nerve and decreased glutamate secretion may be important reasons for early hearing loss in ARHL (Liberman and Kujawa, 2017

MS Grade Trypsin Protease (Thermo Fisher Scientific) was added at a 1:20 enzyme-to-protein ratio (w/w), and digestion was carried out at 37 C for 16 h

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