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According to the 2025 meta-analysis by Alfalasi and colleagues, sublingual B12 showed an approximate 199% mean increase in serum B12 compared to approximately 307% for intramuscular injections

[144] demonstrated that sodium-citrate CQDs could prevent hen egg-white lysosome (HEWL) from forming mature amyloid fibrils, a common model of amyloidogenic protein aggregation [144]