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It is a stress-inducible protein involved in multiple signalling pathways, such as autophagy, where it acts as a cargo receptor for the degradation of ubiquitinated proteins and mitochondria, thus preserving organisms from proteotoxic/oxidative stresses [196, 197]

Chang HH, Bennett AM, Cameron WD, Floro E, Au A, McFaul CM, et al

In a separate article, the same authors demonstrated that the subjects attenuated GH response as a result of hexarelin therapy was reversible following a four-week break from hexarelin injections [23]