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Description

Is DSIP approved by the FDA

Gls-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and atg5Mediated autophagy

Pharmacological inhibition of ATM (e.g., KU-55933) reduces mitochondrial transcription factor A (TFAM) expression in melanoma and breast cancer cells, promotes mtDNA leakage into the cytoplasm, activates the cGAS-STING signaling pathway and downstream cytokine production, and enhances lymphocyte infiltration into the TME, resulting in anti-tumor therapeutic effects (80)