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Table 6 presents the directions of changes in eicosanoid levels influenced by physiological processes, diseases, and therapies, observed both in the skin and in epidermal and dermal cells, including those from healthy individuals and patients with skin diseases

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three non-chiral probes (P2) (2), P3 (3) and P4 (4)

Fatty acids and cholesterol metabolism are independently regulated downstream of AMPK AMPK is a critical enzyme in the cellular response to metabolic stress regulating lipid, cholesterol and glucose metabolism ( ro model predicted AMPK downregulation in the rSCC-61 cells ( Figure 5A )