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Prophylactic carnitine supplementation is also advocated during VPA therapy in high-risk pediatric patients. 13 If you have a history of seizures be sure to ask your doctor before taking L-carnitine

Nature 330 , 401404 (1987)

Simultaneously, glutathione-S-transferase (GST) activity decreases by 72%, reducing the cellular capacity to clear toxic metabolites ( 3.3 Oxidative stress and mitochondrial dysfunction EED-induced oxidative stress represents a central mechanism underlying reproductive toxicity, with mitochondrial dysfunction serving as both cause and consequence of excessive reactive oxygen species production