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R.SterlingS

Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione

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The vulnerability of a recipient to fungal infection is governed by several contributors, mainly immune flaws caused by underlying disorders necessitating an organ transplant (167, 168), organ transplanted type, complications associated with surgery (152, 160, 167), metabolic changes, net state of immunosuppression, infections by viruses, loss of renal function and supplementary therapy to manage graft rejection (152, 165, 169)