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Niemann et al., 2009), calcium homeostasis (Gonzalez-Sanchez et al., 2019), and oxidative stress (Miressi et al., 2021

6 AndujarI.RecioM.GinerR.RosJ

Preprint at bioRxiv (2022)

In the SURMOUNT trials, 15 mg averaged 22.5 percent body weight loss over 72 weeks, while the 5 mg and 10 mg doses landed roughly in the 15 to 20 percent range