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(2020) suggested that MOTS-c could suppress the growth of colorectal cancer cells, indicating its potential as a therapeutic agent in cancer treatment.: While the research on MOTS-c is still in its early stages, the findings so far are promising

Subpopulations of secondary cells are responsive to MOR activation, also producing outward currents

The C-terminal segment takes part in interactions with the N-terminal -helix of the extracellular domain, the extracellular tip of the transmembrane helix 1 of the GLP-1 receptor, and the extracellular loop 1 of the GIP receptor

thus, researchers are trying to increase the tumor permeability by replacing antibodies with smaller peptides and aptamers [143, 207]